Characterization of neurotropic HPAI H5N1 viruses with novel genome constellations and mammalian adaptive mutations in free-living mesocarnivores in CanadaArticle Published on 2023-12-012023-06-14 Journal: Emerging Microbes & Infections [Category] Fulltext, 조류인플루엔자, [키워드] clade 2.3.4.4b H5N1 HPAI mammals Mutation Reassortment. [DOI] 10.1080/22221751.2023.2186608 PMC 바로가기
Highly Pathogenic Avian Influenza A(H5N1) Virus in a Harbor Porpoise, SwedenArticle Published on 2023-04-012023-06-14 Journal: Emerging Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] H5N1 subtype Influenza influenza A virus influenza in birds mammals meningitis/encephalitis pathology Phocoena porpoises Sweden viruses wild animals zoonoses. [DOI] 10.3201/eid2904.221426 PMC 바로가기
Mapping Global Bushmeat Activities to Improve Zoonotic Spillover Surveillance by Using Geospatial ModelingArticle Published on 2023-04-012023-06-14 Journal: Emerging Infectious Diseases [Category] Fulltext, 조류인플루엔자, [키워드] bushmeat conservation deforestation disease outbreaks Ebola hemorrhagic fever mammals mpox Pandemics Surveillance viruses wild meat zoonoses. [DOI] 10.3201/eid2904.221022 PMC 바로가기
Risk of Viral Infectious Diseases from Live Bats, Primates, Rodents and Carnivores for Sale in Indonesian Wildlife MarketsArticle Published on 2022-12-102023-06-22 Journal: Viruses [Category] 조류인플루엔자, [키워드] COVID-19 mammals Nipah one health pandemic wet market Wildlife trade zoonosis. [DOI] 10.3390/v14122756 PMC 바로가기
Remdesivir does not affect mitochondrial DNA copy number or deletion mutation frequency in aged male rats: A short reportArticle Published on 2022-10-262022-11-16 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] Affect age Brain clinical samples coronavirus determine digital PCR DNA Effect Frequency Future hearts Hypothesis individuals inhibiting kidneys liver majority male mammals mitochondrial Mutation no effect not affect Older patients with moderate Remdesivir RNA-directed RNA polymerases rodents SARS-CoV-2 Skeletal muscle Support therapy tissue treated Treatment Viral RNA [DOI] 10.1371/journal.pone.0271850 PMC 바로가기
Multiple Introductions of SARS-CoV-2 Alpha and Delta Variants into White-Tailed Deer in PennsylvaniaArticle Published on 2022-10-262022-11-16 Journal: mBio [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha analyzed animal reservoir bat coronavirus coronavirus COVID-19 epidemic creating deer Delta Delta variants Epidemics example future infection genomic data help Host Human humans identify independent Infection information Lineage mammals management Multiple nasal swab North America observation occur Odocoileus Odocoileus virginianus positive replicate reported reservoir RT-qPCR SARS-CoV-2 SARS-CoV-2 pandemic significantly spike gene susceptible trajectory Transmission transmissions variant vertebrates white-tail deer white-tailed deer whole genome sequence zoonosis zoonosis. [DOI] 10.1128/mbio.02101-22 PMC 바로가기
Zoonotic Disease Risk and Life-History Traits: Are Reservoirs Fast Life Species?Article Published on 2022-09-012023-06-22 Journal: EcoHealth [Category] 조류인플루엔자, [키워드] agricultural intensification Functional traits Host status human health mammals Slow-fast continuum. [DOI] 10.1007/s10393-022-01608-5 PMC 바로가기
Probable Animal-to-Human Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta Variant AY.127 Causing a Pet Shop-Related Coronavirus Disease 2019 (COVID-19) Outbreak in Hong Kong중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 델타 변종 AY.127의 동물 간 전파 가능성이 있어 홍콩에서 애완동물 가게 관련 코로나바이러스 질병 2019(COVID-19) 발생Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, [키워드] 2 acute respiratory syndrome acute respiratory syndrome coronavirus Analysis anti-SARS-CoV-2 antibody causing Chain Reaction collected conducted Contact coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 CoV COVID-19 COVID-19 outbreak Delta delta variant Delta variant AY.127 demonstrated direct contact dwarf enzyme enzyme immunoassay euthanized female Genome genomes Genomic analysis hamster hamsters Hong Kong Human husband immunoassay infect International investigation Laboratory mammals Mesocricetus nucleotide outbreak pandemic virus Patient patients performed pet Phodopus polymerase chain polymerase chain reaction positive Randomly reported respiratory reverse transcription reverse transcription polymerase chain reaction route RT-PCR SARS SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA Sequencing analysis seropositive severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimen Spread strain susceptible tested Transmission transmission of SARS-CoV-2 Transmission. transmitted whole genome Whole genome sequencing [DOI] 10.1093/cid/ciac171 PMC 바로가기 [Article Type] Article
Potential of FX06 to prevent disease progression in hospitalized non-intubated COVID-19 patients – the randomized, EU-wide, placebo-controlled, phase II study design of IXIONClinical Trial Published on 2022-08-192022-10-05 Journal: Trials [Category] SARS, 임상, [키워드] addition Administered Admission capillary Capillary leak Clinical management clinical study code coronavirus COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity Deterioration disease Disease progression double-blinded drop-out Endothelial dysfunction Endpoint enrolled EudraCT Europe France FX06 Germany Hospital stay Hospitalization Hospitalized hospitalized patient Human ICU Inflammation. intravenously Italy lack limitation Lithuania Lung function mammals Mild moderate multicentre Non-intubated occurred outbreak oxygen saturation Patient patient recruitment patients patients receiving placebo peptide per day Placebo placebo-controlled Portugal positive SARS-CoV-2 PCR Potential Prevent prevent disease progression primary endpoint problem proportion protocol randomization Randomized receiving recruitment reduce Romania SARS-CoV-2 secondary Spain stages standard care Study design subject survival systemic inflammation the WHO therapy while [DOI] 10.1186/s13063-022-06609-x PMC 바로가기 [Article Type] Clinical Trial
Calpains in cyanobacteria and the origin of calpains Research Published on 2022-08-162022-10-05 Journal: Scientific Reports [Category] 유전자 메커니즘, [키워드] Anabaena analyses Analysis archaeal Bacteria Bacterial calpain cellular processes cleavage Clusters cysteine protease defined domain Donor enzyme eukaryote eukaryotes eukaryotic explain Human in silico independent information Interaction interaction partner investigated involved mammals Modification Phylogenetic analysis predicted Protein responsible retained selected substrates variety [DOI] 10.1038/s41598-022-18228-2 [Article Type] Research